reviews our current experience with a recently developed device (VU-AMD [ambulatory monitoring device]) for the ambulatory measurement of the electrocardiogram (EKG) and changes in thoracic impedance (ICG) / with this device simultaneous assessment can be made of HR [heart rate], HR variability (HRV), the pre-ejection period (PEP), left ventricular ejection time (LVET), respiration rate (RR) and respiratory sinus arrhythmia (RSA) / PEP and RSA are currently our best noninvasive tools to assess sympathetic and parasympathetic influences on the heart reliability of the VU-AMD was tested in cross-instrument comparison against the “golden standard” of our laboratory devices / to determine feasibility [and validity] of field measurements, a set of 40 Ss has been measured on a 24-hr basis / as a final step we explored the possibilities of this new technique for research into behaviorally induced cardiovascular pathology / in 2 studies, 24-hr profiles of PEP and RSA were obtained with the VU-AMD in S groups with different risk profiles for cardiovascular disease [presence vs absence of insulin resistance syndrome and exercisers vs non-exercisers] (PsycInfo Database Record (c) 2020 APA, all rights reserved)

The wowing need for more advanced ambulatory monitoring has led lo the development of an ambulatory monitor for impedance cardiography (VU-AMD). This paper presents two studies addressing the validity of the VU-AMD. In the first study, the cardiovascular responses of 25 subjects during various conditions were simultaneously recorded with the VU-AMD and a standard laboratory impedance device. Correlations between the responses of the ambulatory and laboratory devices were high, both inter and intraindividually, except lot stroke volume and cardiac output during exercise In the second study, 26 subjects underwent 24-hr monitoring with the VU-AMD. The values obtained with the VU-AMD were realistic and varied in a predictable way over activity and posture. It is concluded that the VU-AMD is a valid device for the measurement of systolic time intervals in real-life situations but its applicability for absolute stroke volume and cardiac output determination remains lo he established.