Short and long-term effects of sham-controlled prefrontal EEG-neurofeedback training in healthy subjects

Objective
In this study we evaluated long-term effects of frontal beta EEG-neurofeedback training (E-NFT) on healthy subjects. We hypothesized that E-NFT can change frontal beta activity in the long-term and that changes in frontal beta EEG activity are accompanied by altered cognitive performance.
Methods
25 healthy subjects were included and randomly assigned to active or sham E-NFT. On average the subjects underwent 15 E-NFT training sessions with a training duration of 45min. Resting-state EEG was recorded prior to E-NFT training (t1) and in a 3-year follow-up (t3).
Results
Compared to sham E-NFT, which was used for the control group, real E-NFT increased beta activity in a predictable way. This increase was maintained over a period of three years post training. However, E-NFT did not result in significantly improved cognitive performance.
Conclusion
Based on our results, we conclude that EEG-NFT can selectively modify EEG beta activity both in short and long-term.
Significance
This is a sham controlled EEG neurofeedback study demonstrating long-term effects in resting state EEG.